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Prognostic impact of KRAS mutant type and MET amplification in metastatic and recurrent gastric cancer patients treated with first-line S-1 plus cisplatin chemotherapy

Receptor tyrosine kinase (RTK)-related genes, including HER2, EGFR, MET, FGFR2 and KRAS, are target molecules that are clinically beneficial in gastric cancer (GC). We investigated the correlation between RTK-related genes and the curative effect of first-line S-1 plus cisplatin (SP) combination che...

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Publicat a:Genes Cancer
Autors principals: Matsusaka, Satoshi, Kobunai, Takashi, Yamamoto, Noriko, Chin, Keisho, Ogura, Mariko, Tanaka, Gotaro, Matsuoka, Kazuaki, Ishikawa, Yuichi, Mizunuma, Nobuyuki, Yamaguchi, Toshiharu
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773703/
https://ncbi.nlm.nih.gov/pubmed/27014419
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