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Implementation of new approaches for generating conventional reassortants for live attenuated influenza vaccine based on Russian master donor viruses

Cold-adapted influenza strains A/Leningrad/134/17/57 (H2N2) and B/USSR/60/69, originally developed in Russia, have been reliable master donors of attenuation for preparing live attenuated influenza vaccines (LAIV). The classical strategy for generating LAIV reassortants is robust, but has some disad...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol Methods
Hauptverfasser: Shcherbik, Svetlana, Pearce, Nicholas, Kiseleva, Irina, Larionova, Natalie, Rudenko, Larisa, Xu, Xiyan, Wentworth, David E., Bousse, Tatiana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773654/
https://ncbi.nlm.nih.gov/pubmed/26519883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2015.10.009
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