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Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

Malignant gliomas constitute one of the most significant areas of unmet medical need, owing to the invariable failure of surgical eradication and their marked molecular heterogeneity. Accumulating evidence has revealed a critical contribution by the Polycomb axis of epigenetic repression. However, a...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Signaroldi, Elena, Laise, Pasquale, Cristofanon, Silvia, Brancaccio, Arianna, Reisoli, Elisa, Atashpaz, Sina, Terreni, Maria Rosa, Doglioni, Claudio, Pruneri, Giancarlo, Malatesta, Paolo, Testa, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773478/
https://ncbi.nlm.nih.gov/pubmed/26923714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10753
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