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In Vivo Biodistribution and Anti-Tumor Efficacy Evaluation of Doxorubicin and Paclitaxel-Loaded Pluronic Micelles Decorated with c(RGDyK) Peptide

The treatment of squamous carcinoma, especially multidrug resistance (MDR) tumors, represents one of the most formidable challenges in oncology. In this study, integrin-mediated Pluronic-based micellar system (c(RGDyK)-FP-DP) was proposed as a drug delivery system to enhance the in vivo anti-tumor e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Yanzuo, Zhang, Wei, Huang, Yukun, Gao, Feng, Fang, Xiaoling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773167/
https://ncbi.nlm.nih.gov/pubmed/26930626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149952
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