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Pluronic mixed micelles overcoming methotrexate multidrug resistance: in vitro and in vivo evaluation
A Pluronic polymeric mixed micelle delivery system was developed in this study by using Pluronic P105 and F127 block copolymers to encapsulate the antitumor compound, methotrexate (MTX). The MTX-loaded Pluronic P105/F127 mixed micelle exhibited the spherical shape with about 22 nm in diameter, high...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630990/ https://ncbi.nlm.nih.gov/pubmed/23620663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S42368 |
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