Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly

Genexol-PM, produced by Samyang Company (Korea) is an excellent preparation of paclitaxel (PTX) for clinical cancer treatment. However, it cannot resolve the issue of multidrug resistance (MDR)—a significant problem in the administration of PTX to cancer patients. To increase the efficacy of Genexol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fan, Zhuoyang, Chen, Cheng, Pang, Xiaoying, Yu, Zhou, Qi, Yang, Chen, Xinyi, Liang, Huihui, Fang, Xiaoling, Sha, Xianyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382049/
https://ncbi.nlm.nih.gov/pubmed/25831130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120129
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