Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly

Genexol-PM, produced by Samyang Company (Korea) is an excellent preparation of paclitaxel (PTX) for clinical cancer treatment. However, it cannot resolve the issue of multidrug resistance (MDR)—a significant problem in the administration of PTX to cancer patients. To increase the efficacy of Genexol...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Fan, Zhuoyang, Chen, Cheng, Pang, Xiaoying, Yu, Zhou, Qi, Yang, Chen, Xinyi, Liang, Huihui, Fang, Xiaoling, Sha, Xianyi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382049/
https://ncbi.nlm.nih.gov/pubmed/25831130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120129
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