NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2

As a genome guardian, p53 maintains genome stability by arresting cells for damage repair or inducing cell apoptosis to eliminate the damaged cells in stress response. Several nucleolar proteins stabilize p53 by interfering Mdm2–p53 interaction upon cellular stress, while other mechanisms by which n...

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Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Liu, Xiaofeng, Tan, Yuqin, Zhang, Chunfeng, Zhang, Ying, Zhang, Liangliang, Ren, Pengwei, Deng, Hongkui, Luo, Jianyuan, Ke, Yang, Du, Xiaojuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772976/
https://ncbi.nlm.nih.gov/pubmed/26882543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540505
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