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Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Increased Sensitivity and Responsiveness

The Ah receptor (AhR)-responsive CALUX (chemically-activated luciferase expression) cell bioassay is commonly used for rapid screening of samples for the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), dioxin-like compounds, and AhR agonists/antagonists. By increasing the number of A...

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Detalhes bibliográficos
Publicado no:Environ Sci Technol
Main Authors: Brennan, Jennifer C., He, Guochun, Tsutsumi, Tomoaki, Zhao, Jing, Wirth, Ed, Fulton, Michael H., Denison, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772899/
https://ncbi.nlm.nih.gov/pubmed/26366531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.5b02906
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