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PAQR3 controls autophagy by integrating AMPK signaling to enhance ATG14L‐associated PI3K activity

The Beclin1–VPS34 complex is recognized as a central node in regulating autophagy via interacting with diverse molecules such as ATG14L for autophagy initiation and UVRAG for autophagosome maturation. However, the underlying molecular mechanism that coordinates the timely activation of VPS34 complex...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Xu, Da‐Qian, Wang, Zheng, Wang, Chen‐Yao, Zhang, De‐Yi, Wan, Hui‐Da, Zhao, Zi‐Long, Gu, Jin, Zhang, Yong‐Xian, Li, Zhi‐Gang, Man, Kai‐Yang, Pan, Yi, Wang, Zhi‐Fei, Ke, Zun‐Ji, Liu, Zhi‐Xue, Liao, Lu‐Jian, Chen, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772855/
https://ncbi.nlm.nih.gov/pubmed/26834238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592864
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