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Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation
The activation of transcriptional coactivators YAP and its paralog TAZ has been shown to promote resistance to anti‐cancer therapies. YAP/TAZ activity is tightly coupled to actin cytoskeleton architecture. However, the influence of actin remodeling on cancer drug resistance remains largely unexplore...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772854/ https://ncbi.nlm.nih.gov/pubmed/26668268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592081 |
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