Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks

Background. Levonorgestrel subdermal implants are preferred contraceptives with an expected failure rate of <1% over 5 years. We assessed the effect of efavirenz- or nevirapine-based antiretroviral therapy (ART) coadministration on levonorgestrel pharmacokinetics. Methods. This nonrandomized, par...

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Détails bibliographiques
Publié dans:Clin Infect Dis
Auteurs principaux: Scarsi, Kimberly K., Darin, Kristin M., Nakalema, Shadia, Back, David J., Byakika-Kibwika, Pauline, Else, Laura J., Dilly Penchala, Sujan, Buzibye, Allan, Cohn, Susan E., Merry, Concepta, Lamorde, Mohammed
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Articles and Commentaries
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772838/
https://ncbi.nlm.nih.gov/pubmed/26646680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ1001
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