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Leptin/LepRb in the Ventral Tegmental Area Mediates Anxiety-Related Behaviors

BACKGROUND: Leptin, an adipose-derived hormone, has been implicated in emotional regulation. We have previously shown that systemic administration of leptin produces anxiolytic-like effects and deletion of the leptin receptor, LepRb, in midbrain dopamine neurons leads to an anxiogenic phenotype. Thi...

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Detalles Bibliográficos
Publicado en:Int J Neuropsychopharmacol
Autores principales: Liu, Jing, Guo, Ming, Lu, Xin-Yun
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772826/
https://ncbi.nlm.nih.gov/pubmed/26438799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv115
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