Gene Expression Markers of Efficacy and Resistance to Cetuximab Treatment in Metastatic Colorectal Cancer: Results from CALGB 80203 (Alliance)

PURPOSE: Formalin-fixed, paraffin-embedded tumor samples from CALGB 80203 were analyzed for expression of EGFR axis–related genes to identify prognostic or predictive biomarkers for cetuximab treatment. PATIENTS AND METHODS: Patients (238 total) with first-line metastatic colorectal cancer (mCRC) we...

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Udgivet i:Clin Cancer Res
Main Authors: Cushman, Stephanie M., Jiang, Chen, Hatch, Ace J., Shterev, Ivo, Sibley, Alexander B., Niedzwiecki, Donna, Venook, Alan P., Owzar, Kouros, Hurwitz, Herbert I., Nixon, Andrew B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772749/
https://ncbi.nlm.nih.gov/pubmed/25520391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2313
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