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Effect of trimethoprim on folate-dependent DNA synthesis in human bone marrow

The effect of trimethoprim in various concentrations was tested on the folate-dependent deoxyuridylate methylation reaction in human bone marrow cultures. A slight effect was demonstrated at a concentration similar to that achieved in the plasma in patients taking the conventional therapeutic dose o...

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Detalhes bibliográficos
Main Authors: Sive, Jane, Green, R., Metz, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC477261/
https://ncbi.nlm.nih.gov/pubmed/5018713
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