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Effect of trimethoprim on folate-dependent DNA synthesis in human bone marrow

The effect of trimethoprim in various concentrations was tested on the folate-dependent deoxyuridylate methylation reaction in human bone marrow cultures. A slight effect was demonstrated at a concentration similar to that achieved in the plasma in patients taking the conventional therapeutic dose o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sive, Jane, Green, R., Metz, J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1972
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC477261/
https://ncbi.nlm.nih.gov/pubmed/5018713
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