Selective erythroid replacement in murine beta-thalassemia using fetal hematopoietic stem cells.

We have explored the application of fetal hematopoietic stem cell (HSC) transplants for cellular replacement in a murine model of beta-thalassemia. Liver-derived HSCs from nonthalassemic syngeneic murine fetal donors were transplanted into nonirradiated neonatal beta-thalassemic recipients. Signific...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bethel, C. A., Murugesh, D., Harrison, M. R., Mohandas, N., Rubin, E. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7980734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10120
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