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Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Mitochondrial fission facilitates cytochrome c release from the intracristae space into the cytoplasm during intrinsic apoptosis, although how the mitochondrial fission factor Drp1 and its mitochondrial receptors Mff, MiD49, and MiD51 are involved in this reaction remains elusive. Here, we analyzed...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Otera, Hidenori, Miyata, Non, Kuge, Osamu, Mihara, Katsuyoshi
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772499/
https://ncbi.nlm.nih.gov/pubmed/26903540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508099
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