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Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Mitochondrial fission facilitates cytochrome c release from the intracristae space into the cytoplasm during intrinsic apoptosis, although how the mitochondrial fission factor Drp1 and its mitochondrial receptors Mff, MiD49, and MiD51 are involved in this reaction remains elusive. Here, we analyzed...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Otera, Hidenori, Miyata, Non, Kuge, Osamu, Mihara, Katsuyoshi
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772499/
https://ncbi.nlm.nih.gov/pubmed/26903540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508099
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