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Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Mitochondrial fission facilitates cytochrome c release from the intracristae space into the cytoplasm during intrinsic apoptosis, although how the mitochondrial fission factor Drp1 and its mitochondrial receptors Mff, MiD49, and MiD51 are involved in this reaction remains elusive. Here, we analyzed...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Otera, Hidenori, Miyata, Non, Kuge, Osamu, Mihara, Katsuyoshi
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772499/
https://ncbi.nlm.nih.gov/pubmed/26903540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508099
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