Chromosome Transfer Induced Aneuploidy Results in Complex Dysregulation of the Cellular Transcriptome in Immortalized and Cancer Cells

Chromosomal aneuploidies are observed in essentially all sporadic carcinomas. These aneuploidies result in tumor-specific patterns of genomic imbalances that are acquired early during tumorigenesis, continuously selected for and faithfully maintained in cancer cells. Although the paradigm of translo...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Upender, Madhvi B., Habermann, Jens K., McShane, Lisa M., Korn, Edward L., Barrett, J. Carl, Difilippantonio, Michael J., Ried, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772432/
https://ncbi.nlm.nih.gov/pubmed/15466185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-04-0474
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