A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells

Development of therapeutics for genetically complex neurodegenerative diseases such as sporadic amyotrophic lateral sclerosis (ALS) has largely been hampered by lack of relevant disease models. Reprogramming of sporadic ALS patients’ fibroblasts into induced pluripotent stem cells (iPSC) and differe...

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Detalhes bibliográficos
Publicado no:Mol Cell Neurosci
Main Authors: Burkhardt, Matthew F, Martinez, Fernando J, Wright, Sarah, Ramos, Carla, Volfson, Dmitri, Mason, Michael, Garnes, Jeff, Dang, Vu, Lievers, Jeffery, Shoukat-Mumtaz, Uzma, Martinez, Rita, Gai, Hui, Blake, Robert, Vaisberg, Eugeni, Grskovic, Marica, Johnson, Charles, Irion, Stefan, Bright, Jessica, Cooper, Bonnie, Nguyen, Leane, Griswold-Prenner, Irene, Javaherian, Ashkan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772428/
https://ncbi.nlm.nih.gov/pubmed/23891805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2013.07.007
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