NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells independent

CD4(+) CD25(+) Foxp3(+) Tregs have been shown to play a central role in immune homeostasis while preventing from fatal inflammatory responses, while Th17 cells have traditionally been recognized as pro-inflammatory mediators implicated in a myriad of diseases. Studies have shown the potential of Tre...

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Publicado no:Sci Rep
Main Authors: Elkhal, Abdallah, Rodriguez Cetina Biefer, Hector, Heinbokel, Timm, Uehara, Hirofumi, Quante, Markus, Seyda, Midas, Schuitenmaker, Jeroen M., Krenzien, Felix, Camacho, Virginia, de la Fuente, Miguel A., Ghiran, Ionita, Tullius, Stefan G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772111/
https://ncbi.nlm.nih.gov/pubmed/26928119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22325
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