Chromosome-scale shotgun assembly using an in vitro method for long-range linkage

Long-range and highly accurate de novo assembly from short-read data is one of the most pressing challenges in genomics. Recently, it has been shown that read pairs generated by proximity ligation of DNA in chromatin of living tissue can address this problem, dramatically increasing the scaffold con...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Putnam, Nicholas H., O'Connell, Brendan L., Stites, Jonathan C., Rice, Brandon J., Blanchette, Marco, Calef, Robert, Troll, Christopher J., Fields, Andrew, Hartley, Paul D., Sugnet, Charles W., Haussler, David, Rokhsar, Daniel S., Green, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772016/
https://ncbi.nlm.nih.gov/pubmed/26848124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.193474.115
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