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Deciphering Mode of Action of Functionally Important Regions in the Intrinsically Disordered Paxillin (Residues 1-313) Using Its Interaction with FAT (Focal Adhesion Targeting Domain of Focal Adhesion Kinase)

Intrinsically disordered proteins (IDPs) play a major role in various cellular functions ranging from transcription to cell migration. Mutations/modifications in such IDPs are shown to be associated with various diseases. Current strategies to study the mode of action and regulatory mechanisms of di...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Neerathilingam, Muniasamy, Bairy, Sneha G., Mysore, Sumukh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771712/
https://ncbi.nlm.nih.gov/pubmed/26928467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150153
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