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GnRH Pulse Frequency Control of Fshb Gene Expression Is Mediated via ERK1/2 Regulation of ICER

The pulsatile release of GnRH regulates the synthesis and secretion of pituitary FSH and LH. Two transcription factors, cAMP-response element-binding protein (CREB) and inducible cAMP early repressor (ICER), have been implicated in the regulation of rat Fshb gene expression. We previously showed tha...

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Détails bibliographiques
Publié dans:Mol Endocrinol
Auteurs principaux: Thompson, Iain R., Ciccone, Nick A., Zhou, Qiongjie, Xu, Shuyun, Khogeer, Ahmad, Carroll, Rona S., Kaiser, Ursula B.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771696/
https://ncbi.nlm.nih.gov/pubmed/26835742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1222
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