GnRH Pulse Frequency-Dependent Stimulation of FSHβ Transcription Is Mediated via Activation of PKA and CREB

Expression of pituitary FSH and LH, under the control of pulsatile GnRH, is essential for fertility. cAMP response element-binding protein (CREB) has been implicated in the regulation of FSHβ gene expression, but the molecular mechanisms by which pulsatile GnRH regulates CREB activation remain poorl...

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Bibliografske podrobnosti
Main Authors: Thompson, Iain R., Ciccone, Nick A., Xu, Shuyun, Zaytseva, Sofiya, Carroll, Rona S., Kaiser, Ursula B.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607701/
https://ncbi.nlm.nih.gov/pubmed/23393127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1281
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