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Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver

Hepcidin is the key regulator of iron absorption and recycling, and its expression is suppressed by red blood cell production. When erythropoiesis is expanded, hepcidin expression decreases. To gain insight into the stage of erythroid differentiation at which the regulation might originate, we measu...

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Dades bibliogràfiques
Publicat a:Exp Hematol
Autors principals: Keel, Siobán B., Doty, Raymond, Liu, Li, Nemeth, Elizabeta, Cherian, Sindhu, Ganz, Tomas, Abkowitz, Janis L.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771411/
https://ncbi.nlm.nih.gov/pubmed/25782630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.03.001
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