Anionic phospholipids stabilize RecA filament bundles in Escherichia coli

We characterize the interaction of RecA with membranes in vivo and in vitro and demonstrate that RecA binds tightly to the anionic phospholipids (aPLs) cardiolipin (CL) and phosphatidylglycerol (PG). Using computational models, we identify two regions of RecA that interact with PG and CL: 1) the N-t...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Rajendram, Manohary, Zhang, Leili, Reynolds, Bradley J., Auer, George K., Tuson, Hannah H., Ngo, Khanh V., Cox, Michael M., Yethiraj, Arun, Cui, Qiang, Weibel, Douglas B.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771187/
https://ncbi.nlm.nih.gov/pubmed/26481664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.009
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