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Anionic phospholipids stabilize RecA filament bundles in Escherichia coli

We characterize the interaction of RecA with membranes in vivo and in vitro and demonstrate that RecA binds tightly to the anionic phospholipids (aPLs) cardiolipin (CL) and phosphatidylglycerol (PG). Using computational models, we identify two regions of RecA that interact with PG and CL: 1) the N-t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Rajendram, Manohary, Zhang, Leili, Reynolds, Bradley J., Auer, George K., Tuson, Hannah H., Ngo, Khanh V., Cox, Michael M., Yethiraj, Arun, Cui, Qiang, Weibel, Douglas B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771187/
https://ncbi.nlm.nih.gov/pubmed/26481664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.009
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