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Generation of Human Monoclonal Autoantibody-Producing Cell Lines by Epstein–Barr Virus Transformation of Autoreactive B Lymphocytes and by Somatic Cell Hybridization Techniques: Application to the Analysis of the Autoimmune B Cell Repertoire()
Epstein–Barr virus (EBV) was used to immortalize human peripheral B lymphocytes committed to the production of autoantibodies in healthy subjects and in patients with various autoimmune diseases. EBV-transformed B lymphocytes producing human monoclonal autoantibodies were fused with the human–mouse...
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| Publicado no: | Immunomethods |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4771017/ https://ncbi.nlm.nih.gov/pubmed/26937163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1058-6687(05)80012-9 |
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