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The B cell repertoire in patients with systemic autoimmune diseases: analysis of Epstein-Barr virus (EBV)-inducible circulating precursors that produce autoantibodies against nuclear ribonucleoprotein (nRNP).

Peripheral blood B cells from patients with systemic autoimmune disease and healthy volunteers were immortalized using EBV and the frequencies of B cell precursors that produced immunoglobulin class-specific antibodies against anti-nRNP, a specific marker for mixed connective tissue disease, were as...

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Bibliographische Detailangaben
Hauptverfasser: Okawa-Takatsuji, M, Aotsuka, S, Uwatoko, S, Sumiya, M, Yokohari, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1554590/
https://ncbi.nlm.nih.gov/pubmed/1333924
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