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Diversified sequences of peptide epitope for same-RNA recognition.

We replaced an essential RNA-binding, 30-amino acid helix-loop in an Escherichia coli tRNA synthetase with an inactive and simplified "generic" sequence having 23 of the 30 amino acids as alanine and serine. Wild-type residues were restored in random combinations to generate a library with...

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Autors principals: Kim, S, Ribas de Pouplana, L, Schimmel, P
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC47710/
https://ncbi.nlm.nih.gov/pubmed/7694278
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