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Functional analysis of peptide motif for RNA microhelix binding suggests new family of RNA-binding domains.
RNA microhelices that recreate the acceptor stems of transfer RNAs are charged with specific amino acids. Here we identify a two-helix pair in alanyl-tRNA synthetase that is required for RNA microhelix binding. A single point mutation at an absolutely conserved residue in this motif selectively disr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170870/ https://ncbi.nlm.nih.gov/pubmed/9736622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.18.5449 |
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