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Heterologous expression of specific K+ channels in T lymphocytes: functional consequences for volume regulation.

It has been postulated that the K+ channel isoform Kv1.3 plays a role in regulatory volume decrease (RVD) in response to hypotonic shock. We show that a mouse cytotoxic T-lymphocyte line, CTLL-2, is devoid of voltage-dependent K+ channels and is unable to volume regulate. Transient transfection of t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Deutsch, C, Chen, L Q
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10036
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