Heterologous expression of specific K+ channels in T lymphocytes: functional consequences for volume regulation.
It has been postulated that the K+ channel isoform Kv1.3 plays a role in regulatory volume decrease (RVD) in response to hypotonic shock. We show that a mouse cytotoxic T-lymphocyte line, CTLL-2, is devoid of voltage-dependent K+ channels and is unable to volume regulate. Transient transfection of t...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1993
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10036 |
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