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Hippocampal infusions of apolipoprotein E peptides induce long-lasting cognitive impairment
The inheritance of the ε4 allele of apolipoprotein E (ApoE4) and cholinergic system dysfunction have long been associated with the pathology of Alzheimer’s disease (AD). Recently, in vitro studies have established a direct link between ApoE and cholinergic function in that synthetic peptides contain...
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| Publicado no: | Brain Res Bull |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770792/ https://ncbi.nlm.nih.gov/pubmed/19185602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2009.01.003 |
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