Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo

Trastuzumab, a humanized monoclonal antibody targeting HER2, has demonstrated clinical benefits for women with HER2-positive breast cancer; however, trastuzumab resistance remains the biggest clinical challenge. In this study, results showed that tunicamycin, an inhibitor of N-glycosylation, synergi...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Han, Xiqian, Zhang, Xiaobing, Li, Hui, Huang, Shengshi, Zhang, Shu, Wang, Fengshan, Shi, Yikang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770746/
https://ncbi.nlm.nih.gov/pubmed/26498681
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