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MYC-driven aggressive B-cell lymphomas: biology, entity, differential diagnosis and clinical management

MYC, a potent oncogene located at chromosome locus 8q24.21, was identified initially by its involvement in Burkitt lymphoma with t(8;14)(q24;q32). MYC encodes a helix-loop-helix transcription factor that accentuates many cellular functions including proliferation, growth and apoptosis. MYC alteratio...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Cai, Qingqing, Medeiros, L. Jeffrey, Xu, Xiaolu, Young, Ken H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770723/
https://ncbi.nlm.nih.gov/pubmed/26416427
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