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The K(+)-dependent GTPase Nug1 is implicated in the association of the helicase Dbp10 to the immature peptidyl transferase centre during ribosome maturation

Ribosome synthesis employs a number of energy-consuming enzymes in both eukaryotes and prokaryotes. One such enzyme is the conserved circularly permuted GTPase Nug1 (nucleostemin in human). Nug1 is essential for 60S subunit assembly and nuclear export, but its role and time of action during maturati...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Manikas, Rizos-Georgios, Thomson, Emma, Thoms, Matthias, Hurt, Ed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770245/
https://ncbi.nlm.nih.gov/pubmed/26823502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw045
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