Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity

Glioblastoma (GBM) is a deadly brain cancer, for which few effective drug treatments are available. Several studies have used zebrafish models to study GBM, but a standardized approach to modeling GBM in zebrafish was lacking to date, preventing comparison of data across studies. Here, we describe a...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Welker, Alessandra M., Jaros, Brian D., Puduvalli, Vinay K., Imitola, Jaime, Kaur, Balveen, Beattie, Christine E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Resource Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770147/
https://ncbi.nlm.nih.gov/pubmed/26659251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022921
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