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A new gestational diabetes mellitus model: hyperglycemia-induced eye malformation via inhibition of Pax6 in the chick embryo

Gestational diabetes mellitus (GDM) is one of the leading causes of fetal malformations. However, few models have been developed to study the underlying mechanisms of GDM-induced fetal eye malformation. In this study, a high concentration of glucose (0.2 mmol per egg) was injected into the air sac o...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: Zhang, Shi-Jie, Li, Yi-Fang, Tan, Rui-Rong, Tsoi, Bun, Huang, Wen-Shan, Huang, Yi-Hua, Tang, Xiao-Long, Hu, Dan, Yao, Nan, Yang, Xuesong, Kurihara, Hiroshi, Wang, Qi, He, Rong-Rong
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770145/
https://ncbi.nlm.nih.gov/pubmed/26744353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022012
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