A new gestational diabetes mellitus model: hyperglycemia-induced eye malformation via inhibition of Pax6 in the chick embryo

Gestational diabetes mellitus (GDM) is one of the leading causes of fetal malformations. However, few models have been developed to study the underlying mechanisms of GDM-induced fetal eye malformation. In this study, a high concentration of glucose (0.2 mmol per egg) was injected into the air sac o...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Zhang, Shi-Jie, Li, Yi-Fang, Tan, Rui-Rong, Tsoi, Bun, Huang, Wen-Shan, Huang, Yi-Hua, Tang, Xiao-Long, Hu, Dan, Yao, Nan, Yang, Xuesong, Kurihara, Hiroshi, Wang, Qi, He, Rong-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770145/
https://ncbi.nlm.nih.gov/pubmed/26744353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022012
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