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Mcl-1 Regulates Effector and Memory CD8 T-Cell Differentiation During Acute Viral Infection

Mcl-1, an anti-apoptotic member of Bcl-2 family maintains cell viability during clonal expansion of CD8 T cells, but the cell intrinsic role of Mcl-1 in contraction of effectors or the number of memory CD8 T cells is unknown. Mcl-1 levels decline profoundly during the contraction phase but rebound t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Virology
मुख्य लेखकों: Kim, Eui Ho, Neldner, Brandon, Gui, Jingang, Craig, Ruth W., Suresh, M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769930/
https://ncbi.nlm.nih.gov/pubmed/26855329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.01.008
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