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Mcl-1 Regulates Effector and Memory CD8 T-Cell Differentiation During Acute Viral Infection
Mcl-1, an anti-apoptotic member of Bcl-2 family maintains cell viability during clonal expansion of CD8 T cells, but the cell intrinsic role of Mcl-1 in contraction of effectors or the number of memory CD8 T cells is unknown. Mcl-1 levels decline profoundly during the contraction phase but rebound t...
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| Publicado no: | Virology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769930/ https://ncbi.nlm.nih.gov/pubmed/26855329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.01.008 |
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