Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

Transcription factors (TFs) are thought to function with partners to achieve specificity and precise quantitative outputs. In the developing heart, heterotypic TF interactions, such as between the T-box TF TBX5 and the homeodomain TF NKX2-5, have been proposed as a mechanism for human congenital hea...

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Udgivet i:Cell
Main Authors: Luna-Zurita, Luis, Stirnimann, Christian U., Glatt, Sebastian, Kaynak, Bogac L., Thomas, Sean, Baudin, Florence, Samee, Md Abul Hassan, He, Daniel, Small, Eric M., Mileikovsky, Maria, Nagy, Andras, Holloway, Alisha K., Pollard, Katherine S., Müller, Christoph W., Bruneau, Benoit G.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769693/
https://ncbi.nlm.nih.gov/pubmed/26875865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.01.004
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