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Defects in Retinal Pigment Epithelial Cell Proteolysis and the Pathology Associated with Age-related Macular Degeneration

Maintenance of protein homeostasis, also referred to as “Proteostasis”, integrates multiple pathways that regulate protein synthesis, folding, translocation, and degradation. Failure in proteostasis may be one of the underlying mechanisms responsible for the cascade of events leading to age-related...

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Detalhes bibliográficos
Publicado no:Prog Retin Eye Res
Main Authors: Ferrington, Deborah A., Sinha, Debasish, Kaarniranta, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769684/
https://ncbi.nlm.nih.gov/pubmed/26344735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preteyeres.2015.09.002
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