Imaging the intratumoral-peritumoral extracellular pH gradient of gliomas

Solid tumors have acidic extracellular pH (pH(e)) but near neutral intracellular pH (pH(i)). Because acidic pH(e) milieu is conducive to tumor growth and builds resistance to therapy, simultaneous mapping of pH(e) inside and outside the tumor (i.e., intratumoral-peritumoral pH(e) gradient) fulfills...

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Detaylı Bibliyografya
Yayımlandı:NMR Biomed
Asıl Yazarlar: Coman, Daniel, Huang, Yuegao, Rao, Jyotsna U., De Feyter, Henk M., Rothman, Douglas L., Juchem, Christoph, Hyder, Fahmeed
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769673/
https://ncbi.nlm.nih.gov/pubmed/26752688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3466
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