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Imaging the intratumoral-peritumoral extracellular pH gradient of gliomas
Solid tumors have acidic extracellular pH (pH(e)) but near neutral intracellular pH (pH(i)). Because acidic pH(e) milieu is conducive to tumor growth and builds resistance to therapy, simultaneous mapping of pH(e) inside and outside the tumor (i.e., intratumoral-peritumoral pH(e) gradient) fulfills...
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| Publié dans: | NMR Biomed |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769673/ https://ncbi.nlm.nih.gov/pubmed/26752688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3466 |
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