Imaging the intratumoral-peritumoral extracellular pH gradient of gliomas

Solid tumors have acidic extracellular pH (pH(e)) but near neutral intracellular pH (pH(i)). Because acidic pH(e) milieu is conducive to tumor growth and builds resistance to therapy, simultaneous mapping of pH(e) inside and outside the tumor (i.e., intratumoral-peritumoral pH(e) gradient) fulfills...

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Publicado en:NMR Biomed
Autores principales: Coman, Daniel, Huang, Yuegao, Rao, Jyotsna U., De Feyter, Henk M., Rothman, Douglas L., Juchem, Christoph, Hyder, Fahmeed
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769673/
https://ncbi.nlm.nih.gov/pubmed/26752688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3466
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