Effect of pH changes on the binding of vitamin B(12) by intrinsic factor

The binding of vitamin B(12) by human gastric juice has been found to be pH dependent. Maximum binding occurs between pH 6·5 and 10. Outside this pH range the vitamin B(12)-binding ability of human gastric juice decreases and at pH below 2 or above 12·2 this drops sharply to about 10 to 15% of the m...

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Pubblicato in:	J Clin Pathol
Autori principali:	Shum, Hing-Yan, O'Neill, Barry J., Streeter, Arthur M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMJ Publishing Group 1971
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC476962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5103294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.24.3.239
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