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Effect of pH changes on the binding of vitamin B(12) by intrinsic factor

The binding of vitamin B(12) by human gastric juice has been found to be pH dependent. Maximum binding occurs between pH 6·5 and 10. Outside this pH range the vitamin B(12)-binding ability of human gastric juice decreases and at pH below 2 or above 12·2 this drops sharply to about 10 to 15% of the m...

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Detalhes bibliográficos
Main Authors: Shum, Hing-Yan, O'Neill, Barry J., Streeter, Arthur M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC476962/
https://ncbi.nlm.nih.gov/pubmed/5103294
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