Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice

BACKGROUND: Influenza A virus is a zoonotic pathogen that poses a major threat to human and animal health. The severe course of influenza infection is not only influenced by viral virulence factors but also by individual differences in the host response. To determine the extent to which the genetic...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Leist, Sarah R., Pilzner, Carolin, van den Brand, Judith M.A., Dengler, Leonie, Geffers, Robert, Kuiken, Thijs, Balling, Rudi, Kollmus, Heike, Schughart, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769537/
https://ncbi.nlm.nih.gov/pubmed/26921172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2483-y
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