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Functional roles of the nucleotide-binding folds in the activation of the cystic fibrosis transmembrane conductance regulator.

The cystic fibrosis transmembrane conductance regulator (CFTR), a member of the traffic ATPase superfamily, possesses two putative nucleotide-binding folds (NBFs). The NBFs are sufficiently similar that sequence alignment of highly conserved regions can be used to identify analogous residues in the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Smit, L S, Wilkinson, D J, Mansoura, M K, Collins, F S, Dawson, D C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7694298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.9963
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